Evidence-Based Practice Paper
Gregory Cahill
Lakeview College of Nursing
July 26, 2012

EVIDENCE-BASED PRACTICE PAPER
	This paper will review the protocol from “Putting Evidence into Practice: Prevention and management of Bleeding in Patients with Cancer”.  Many cancer patients experience bleeding as a direct result of the cancer or as a secondary affect related to treatment.  This protocol evaluates measures to prevent and manage bleeding in cancer patients.  The study reviewed 14 prevention/treatment options focusing on the outcomes of platelet count, morbidity, quality of life and mortality (Damron, Brant, Belansky, Friend, Samsonow & Schaal, 2009).  The study reviewed literature and divided it into three subgroups; antifibrinolytic and pharmacology, blood products and non-pharmacology, and procedures (Damron et al., 2009). The study used two rating systems to rate the strength of the evidence for each intervention from one being the strongest evidence and eight having the least evidence and in the other rating system one was the best evidence and 3 being the least (Damron et al., 2009).  The research was then manufactured into three categories; recommended for practice, likely to be effective and expert opinion.
	Platelet transfusion therapy and mercapto ethane sulfonate sodium (MESNA) are recommended for practice based on the situation of the patient and treatment.   

Damron, B., Brant, J., Belansky, H., Friend, P., Samsonow, S., & Schaal, A. (2009). Putting evidence into practice: Prenention and management of bleeding in patien ts with cancer. Clinical Journal of Oncology Nursing, 13(5), doi: 10.1188/09.CJON.573-583